Our vision is a world in which no one suffers or dies from a vaccine-preventable disease.

Welcome to the Sanofi Pasteur VaxDesign Research Blood Donor Program

Sanofi Pasteur VaxDesign Corporation, one of central Florida's leading biotechnology research companies, is looking for volunteers between the ages of 18 and 85 to take part in an investigational study to aid in the development of an artificial immune system to test vaccine formulations.

In order to perform studies of human health and disease, VaxDesign needs to use human blood samples taken from healthy donors. To help investigators in doing this research, VaxDesign has established a "Research Blood Donor Program." This study has been approved by an Adavar Institutional Review Board dedicated to protecting human research participants’ rights (Protocol 0906009). You are being asked to take part in this program and donate your blood for use in research studies done by VaxDesign. Blood products collected as part of this program will be obtained through a procedure called mononuclear cell (MNC) apheresis donation or whole blood collection.

If you choose to participate in this research study, you will be asked to donate whole blood or apheresis units. Your participation could involve up to 8 sessions per year. Whole blood donations typically take 1 hour or less; apheresis sessions can last approximately 3-4 hours.

Participation Requirements

In order to participate you must be 18-85 years old, in good health, not pregnant, attend an orientation session, and pass disease screens each time you donate.

Parts of your blood will be used in VaxDesign's MIMIC® immunotherapy testing system. The MIMIC® System will be challenged with different vaccines to indicate an immune response in the device. Other tests could also be done on your blood cells in an effort to advance and improve our understanding of immunology.

Orientation

As a part of the application process to participate in the Research Blood Donor Program you will be asked to attend an orientation session. At this session you will fill out several forms including the consent form for this study. You will also listen to a short presentation describing the study, the risks, and compensation. You can find the slides for the presentation here. Finally, a representative from OneBlood will take a small sample of blood to do the initial blood screens to determine your eligibility in the research study. You should carefully consider the forms and presentation before agreeing to participate in the study. Please allow 2 hours for the orientation.

Whole blood collection

You will be asked to lie on a reclining collection chair for this procedure. A needle will be placed into the vein just below the bend in your elbow. One pint of whole blood will be drawn per collection. The actual collection process generally takes less than 15 minutes. After the procedure, you will be asked to stay for observation for 10 to 15 minutes.

Whole blood donations are generally very safe and are no different from a normal blood draw. Side effects associated with whole blood donations are lightheadedness, dizziness, fainting, or seizures. There could be nerve damage or infection at the injection site. There is also a risk of experiencing temporary low blood pressure. Please notify the staff right away if you experience any of these.

You may not take part in this study if you are breastfeeding, are pregnant, think that you may be pregnant, or are trying to get pregnant. If you are pregnant or breastfeeding, there may be risks to you and the baby that are not known at this time.

Apheresis blood collection

You will be asked to lie on a reclining collection chair for this procedure. Needles will placed into veins just below the bend of both elbows. Blood will be drawn from one arm, pass through a blood cell separator instrument and returned to your body through the other arm. As the blood passes through the machine, white blood cells are collected in a sterile process, while the remaining red cells, platelets, and plasma are returned to the body. To keep the blood from clotting during the procedure, an anticoagulant is added to blood using a saline drip. The collection process generally takes about 3 hours. Upon completing the procedure, you will be asked to stay for observation for 10 to 15 minutes.

Apheresis donations are generally very safe, and side effects are rare. Pain and bruising may occur at the needle placement sites. Very rarely, following any procedure, there may be temporary or permanent nerve damage or infection at the needle placement sites. Donors may also develop numbness and tingling around their mouths and fingertips. This effect is associated with the citrate anticoagulant, which binds up calcium to prevent clotting. This effect is temporary and can be lessened or prevented by taking a calcium supplement prior or during the donation. Some donors feel a slight chill during donation because the blood is cooler when it is returned. As with whole blood collections, temporary lowering of the blood pressure may develop, and lightheadedness, dizziness, fainting, and even seizures may occur. However, because the apheresis procedure removes only the leukocytes from your blood and returns the other components (red blood cells, platelets, and plasma), possible side effects experienced during whole blood donations (such as lightheadedness) are minimized.

You may not take part in this study if you are breastfeeding, are pregnant, think that you may be pregnant, or are trying to get pregnant. If you are pregnant or breastfeeding, there may be risks to you and the baby that are not known at this time.

Compensation

All tests, procedures and visits required by the study are provided at no cost to you. The sponsor, VaxDesign Corporation, pays for them.

In appreciation for your time, you will receive compensation of $50 per whole blood donation and $200 per apheresis donation. Your participation could involve up to 8 sessions per year.

Sanofi Pasteur VaxDesign

Email: info@vaxdesign.com
Phone: (407) 243-5600
Fax: (407) 243-5605

OneBlood Center - Donation Site

Address:
8669 Commodity Circle
Orlando, FL 32819

Phone: (407) 248-5009